Key result
Deep subcutaneous adipose tissue may play a deleterious role in cardiometabolic health, though its specific relationship with dietary intake and cardiovascular disease outcomes remains poorly understood.
This editorial highlights the distinct metabolic role of deep subcutaneous adipose tissue in cardiometabolic risk and underscores the need for further research into how diet influences specific abdominal fat depots and cardiovascular outcomes.
that DSAT may play a deleterious role in mechanisms related to cardiometabolic health. Diet plays a crucial role in abdominal fat accumulation. In a longitudinal analysis of the Framingham Heart Study, the lowest diet quality, evaluated by adherence to a Mediterranean-style diet score, was associated with the greatest abdominal SAT. 8 In addition, in a systematic review of observational and controlled intervention studies, 9 the quantity and quality of carbohydrates, protein, fat, and dietary fiber, as well as the intake of calcium, alcohol, phytochemicals, probiotics, cereal-based foods, sweets, sugar-sweetened beverages, between-meal snacks, and dietary patterns, were related to VAT and/ or SAT. Thus, while it is clear that dietary exposure is related to abdominal fat depots, the relationship among diet, abdominal adiposity, and CVD outcomes is poorly understood.
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Weschenfelder et al. (2021) conducted an editorial in Cardiovascular disease and Acute Coronary Syndrome. Dietary intake and lifestyle factors was evaluated on Deep subcutaneous adipose tissue (DSAT) and cardiovascular disease risk. Deep subcutaneous adipose tissue may play a deleterious role in cardiometabolic health, though its specific relationship with dietary intake and cardiovascular disease outcomes remains poorly understood.
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