Key result
The Peguero-Lo Presti ECG criterion showed the highest sensitivity (62.5%) and accuracy (AUC 0.787; 95% CI 0.698-0.876; P<0.001) for detecting left ventricular hypertrophy in octogenarians.
Why the study?
Existing electrocardiographic criteria for LVH have low sensitivity; the newer Peguero-Lo Presti criterion showed higher sensitivity, but prospective evaluation in octogenarians was needed.
Does the Peguero-Lo Presti ECG criterion improve the diagnostic sensitivity for left ventricular hypertrophy in octogenarian outpatients compared to other established ECG criteria?
Observational (n=119)
Does the Peguero-Lo Presti ECG criterion improve the diagnostic sensitivity for left ventricular hypertrophy in octogenarian outpatients compared to other established ECG criteria?
Effect estimate: AUC 0.787 (95% CI 0.698-0.876)
p-value: p=< .001
The Peguero-Lo Presti ECG criterion provides superior sensitivity and overall diagnostic accuracy for detecting left ventricular hypertrophy in octogenarians compared to traditional ECG criteria.
May support Peguero-Lo Presti criterion for LVH screening in octogenarians; leaves open prospective validation against imaging.
BACKGROUND: Although there are several electrocardiographic (ECG) diagnostic criteria for identifying left ventricular hypertrophy (LVH), the sensitivity of these criteria remains low. Recently, the Peguero-Lo Presti criterion provides a higher sensitivity than the current criteria. We aimed to test this ECG criterion prospectively, in the octogenarian population. METHODS: We prospectively enrolled outpatients over 80 years of age who were referred to our echocardiography laboratory. The Peguero-Lo Presti criterion was assessed along with other established ECG criteria. Left ventricular mass was calculated by echocardiography. Performance of ECG indices in diagnosing LVH were evaluated. RESULTS: Overall, 119 patients were included in the study. The sensitivity and specificity of the Peguero-Lo Presti criterion were 62.5% and 87.3%, respectively. In addition, the highest sensitivity belonged to the Peguero-Lo Presti criterion, and the highest AUC value was also seen in this criterion (AUC: 0.787, 95% CI, 0.698-0.876, P < .001). CONCLUSION: The Peguero-Lo Presti criteria showed the highest sensitivity for LVH detection, and it outperformed the other validated criteria in this octogenarian population. The Peguero-Lo Presti criteria seemed to be more effective for diagnosing LVH in this setting.
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Gürdal et al. (2020) conducted an observational in Left ventricular hypertrophy (n=119). Peguero-Lo Presti criterion vs. Other established ECG criteria was evaluated on Diagnosis of left ventricular hypertrophy (AUC 0.787, 95% CI 0.698-0.876, p=< .001). The Peguero-Lo Presti ECG criterion showed the highest sensitivity (62.5%) and accuracy (AUC 0.787; 95% CI 0.698-0.876; P<0.001) for detecting left ventricular hypertrophy in octogenarians.
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