Key result
Off-label thrombolysis for ischemic stroke resulted in symptomatic intracranial hemorrhage in 6.95% and extracranial hemorrhage in 6.22% of patients.
Why the study?
Does off-label thrombolysis cause excessive hemorrhagic complications in patients with ischemic stroke?
Population
273 patients with ischemic stroke treated with off-label thrombolysis
Design
Review
Authors
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The bleeding risk associated with off-label thrombolysis for ischemic stroke may not be as high as presumed, though a registry is needed to overcome reporting biases.
Systematic Review (n=273)
Does off-label thrombolysis cause excessive hemorrhagic complications in patients with ischemic stroke?
The bleeding risk associated with off-label thrombolysis for ischemic stroke may not be as high as presumed, though a registry is needed to overcome reporting biases.
Aleu et al. (2006) conducted a systematic review in Ischemic stroke (n=273). Off-label thrombolysis was evaluated on Symptomatic intracranial hemorrhage. Off-label thrombolysis for ischemic stroke resulted in symptomatic intracranial hemorrhage in 6.95% and extracranial hemorrhage in 6.22% of patients.
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