Key result
Cardiac rehabilitation was positively associated with temporal improvements in health-related quality of life up to 12 months post-AMI (coefficient 2.12; 95% CI 0.68-3.55).
Why the study?
To evaluate how cardiac rehabilitation and physical activity associate with temporal changes in health-related quality of life following acute myocardial infarction.
Does cardiac rehabilitation and physical activity improve health-related quality of life in patients following acute myocardial infarction?
Cohort (n=4,570)
Yes
Does cardiac rehabilitation and physical activity improve health-related quality of life in patients following acute myocardial infarction?
Mean Difference: 2.12 (95% CI 0.68–3.55)
Cardiac rehabilitation and physical activity of ≥150 min/week are independently associated with significant improvements in health-related quality of life up to 12 months after acute myocardial infarction.
May support post-AMI cardiac rehabilitation referral; leaves open causal effects pending randomized confirmation.
OBJECTIVE: To study the association of cardiac rehabilitation and physical activity with temporal changes in health-related quality of life (HRQoL) following acute myocardial infarction (AMI). METHODS: Evaluation of the Methods and Management of Acute Coronary Events-3 is a nationwide longitudinal prospective cohort study of 4570 patients admitted with an AMI between 1 November 2011 and 17 September 2013. HRQoL was estimated using EuroQol 5-Dimension-3 Level Questionnaire at hospitalisation, 30 days, and 6 and 12 months following hospital discharge. The association of cardiac rehabilitation and self-reported physical activity on temporal changes in HRQoL was quantified using inverse probability of treatment weighting propensity score and multilevel regression analyses. RESULTS: Cardiac rehabilitation attendees had higher HRQoL scores than non-attendees at 30 days (mean EuroQol 5-Visual Analogue Scale (EQ-VAS) scores: 71.0 (SD 16.8) vs 68.6 (SD 19.8)), 6 months (76.0 (SD 16.4) vs 70.2 (SD 19.0)) and 12 months (76.9 (SD 16.8) vs 70.4 (SD 20.4)). Attendees who were physically active ≥150 min/week had higher HRQoL scores compared with those who only attended cardiac rehabilitation at 30 days (mean EQ-VAS scores: 79.3 (SD 14.6) vs 70.2 (SD 17.0)), 6 months (82.2 (SD 13.9) vs 74.9 (SD 16.7)) and 12 months (84.1 (SD 12.1) vs 75.6 (SD 17.0)). Cardiac rehabilitation and self-reported physical activity of ≥150 min/week were each positively associated with temporal improvements in HRQoL (coefficient: 2.12 (95% CI 0.68 to 3.55) and 4.75 (95% CI 3.16 to 6.34), respectively). CONCLUSIONS: Cardiac rehabilitation was independently associated with temporal improvements in HRQoL at up to 12 months following hospitalisation, with such changes further improved in patients who were physically active.
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Hurdus et al. (2020) conducted a cohort in Acute myocardial infarction (AMI) (n=4,570). Cardiac rehabilitation vs. Non-attendees was evaluated on Temporal changes in health-related quality of life (HRQoL) (coefficient 2.12, 95% CI 0.68 to 3.55). Cardiac rehabilitation was positively associated with temporal improvements in health-related quality of life up to 12 months post-AMI (coefficient 2.12; 95% CI 0.68-3.55).
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