What question did this study set out to answer?

To evaluate epidemiological shifts, microbiological profiles, and independent predictors of mortality in patients admitted with infective endocarditis across two consecutive decades.

June 19, 2018Scandinavian Journal of Infectious Diseases

Infective endocarditis in Western Norway: a 20-year retrospective survey

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Authors

SJStina JordalHaukeland University Hospital BKBård Reiakvam KittangHaraldsplass Diakonale Sykehus PSPirjo‐Riitta SalminenHaukeland University Hospital

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Implication

Retrospective study reveals rising incidence and shifting microbiology in infective endocarditis admissions, indicating new challenges from enterococcal infections and bioprostheses.

Key Points

To evaluate epidemiological shifts, microbiological profiles, and independent predictors of mortality in patients admitted with infective endocarditis across two consecutive decades.
Analyzed characteristics of 706 infective endocarditis admissions in Western Norway across two periods: 1996–2005 versus 2006–2015.
Compared categorical variables using the Chi-square test, age differences using the t-test, and overall survival using multiple Cox regression models reported by hazard ratios.
Mean annual incidence of infective endocarditis increased from 4.6 to 7.4 per 100,000 inhabitants (rate ratio: 1.97, 95% CI: 1.52–2.56, p < 0.001).
Enterococcal infections grew from 3.7% to 13.0% (p < 0.001), with non-viridans streptococci, enterococci, and Staphylococcus aureus independently predicting higher mortality.
Intravenous drug users increased from 16.5% to 23.5% (p = 0.015) alongside higher aortic valve involvement (p = 0.023), while biological prosthetic valve endocarditis rose from 9.4% to 22.1% (p < 0.001) as mechanical cases fell from 18.7% to 8.9% (p < 0.001).

Cite This Study

Jordal et al. (2018) studied this question.

synapsesocial.com/papers/6a7dbfa7c6a151781133a00e https://doi.org/10.1080/23744235.2018.1482419

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Implication

Retrospective study reveals rising incidence and shifting microbiology in infective endocarditis admissions, indicating new challenges from enterococcal infections and bioprostheses.

Infective endocarditis in Western Norway: a 20-year retrospective survey

Discussion

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Implication

Key Points

Cite This Study

Infective endocarditis in Western Norway: a 20-year retrospective survey

Discussion

Member takes

Implication

Key Points

Cite This Study

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