Why the study?
Can a spectrophotometric kinetic assay accurately detect and quantify creatine kinase MB isoenzyme activity in sera with normal or slightly increased total creatine kinase?
Population
Sera from 14 patients with acute myocardial infarction, healthy lab technicians, patients with noncardiac…
Design
Other
Follow-up
Up to 5 days
Authors
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Supports rapid CK-MB quantification for AMI diagnosis; leaves open validation before routine clinical use.
Can a spectrophotometric kinetic assay accurately detect and quantify creatine kinase MB isoenzyme activity in sera with normal or slightly increased total creatine kinase?
The described spectrophotometric kinetic assay provides a rapid, specific, and sensitive method for quantifying creatine kinase MB isoenzyme activity to aid in the diagnosis of acute myocardial infarction.
Mercer et al. (1975) studied this question.
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