Key result
Aspirin resistance appears to be associated with poor clinical outcomes, although the lack of a standardized definition and comparable laboratory methods limits specific treatment recommendations.
Why the study?
Is aspirin resistance associated with poor clinical outcomes in patients treated with aspirin?
Population
Patients treated with aspirin for arterial thrombotic events
Design
Systematic_review
Authors
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Urges caution against routine resistance testing to guide therapy; leaves open standardized assays to confirm prognostic value and enable targeted trials.
Systematic Review
Is aspirin resistance associated with poor clinical outcomes in patients treated with aspirin?
Aspirin resistance is associated with worse clinical outcomes, but the lack of standardized testing methods limits the ability to make specific treatment recommendations.
Pusch et al. (2008) conducted a systematic review in Aspirin resistance in patients at risk for arterial thrombotic events. Aspirin resistance was evaluated on Clinical outcome. Aspirin resistance appears to be associated with poor clinical outcomes, although the lack of a standardized definition and comparable laboratory methods limits specific treatment recommendations.
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