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Review the clinical applications and diagnostic performance of white blood cell SPECT/CT, [18F]FDG-PET/CT, and CT angiography in infective endocarditis and cardiovascular implantable electronic device infections.

June 10, 2025Heart Failure ClinicsOpen Access

Radionuclide Imaging of Infective Endocarditis

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Review the clinical applications and diagnostic performance of white blood cell SPECT/CT, [18F]FDG-PET/CT, and CT angiography in infective endocarditis and cardiovascular implantable electronic device infections.
Reviewed multimodal imaging protocols combining echocardiography, white blood cell SPECT/CT, [18F]FDG-PET/CT, and coronary CT angiography.
Assessed diagnostic frameworks integrating clinical signs, microbiological findings, and advanced imaging for infected valves and cardiac devices.
Molecular imaging with white blood cell SPECT/CT and [18F]FDG-PET/CT enhances diagnostic sensitivity for infections involving heart valves and cardiovascular implantable electronic devices.
Integrating radionuclide imaging with CT angiography facilitates the early identification of extracardiac spread, including septic emboli and metastatic infections.

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Implication

Review highlights the utility of PET/CT, SPECT/CT, and CTA in infective endocarditis, indicating their value for identifying valve and cardiovascular implantable electronic device infections.

Cite This Study

Ferro et al. (2025) studied this question.

synapsesocial.com/papers/6a7dcb1b699b737ada99a0b4 https://doi.org/10.1016/j.hfc.2025.01.008

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Implication

Review highlights the utility of PET/CT, SPECT/CT, and CTA in infective endocarditis, indicating their value for identifying valve and cardiovascular implantable electronic device infections.

Radionuclide Imaging of Infective Endocarditis

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Discussion

Implication

Cite This Study

Radionuclide Imaging of Infective Endocarditis

Key Points

Discussion

Implication

Cite This Study

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