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September 1, 1998Phlebology The Journal of Venous Disease

Risk of and Prophylaxis for Venous Thromboembolism in Hospital Patients

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Why the study?

Does thromboprophylaxis reduce the incidence of postoperative deep vein thrombosis and pulmonary embolism in hospital patients?

Population

Hospital patients at risk for venous thromboembolism, including those undergoing orthopaedic surgery, major…

Comparison

Thromboprophylaxis vs Alternative prophylaxis strategies or no…

Design

Systematic_review

Discussion

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Implication

Thromboprophylaxis should be routine postoperatively; reinforces LMWH preference over UFH in orthopaedic, trauma, and general surgery.

Structured PICO

Does thromboprophylaxis reduce the incidence of postoperative deep vein thrombosis and pulmonary embolism in hospital patients?

P
Population
Hospital patients at risk for venous thromboembolism, including those undergoing orthopaedic surgery, major trauma, and general surgery
I
Intervention
Thromboprophylaxis (including low-molecular-weight heparins [LMWH] and unfractionated heparin [UFH])
C
Comparator
Alternative prophylaxis strategies (e.g., UFH vs LMWH) or no prophylaxis
O
Outcome
Incidence of postoperative deep vein thrombosis and pulmonary embolismhard clinical

This systematic review highlights the efficacy of VTE prophylaxis in hospital patients and supports the preferred use of LMWH over UFH in high-risk surgical and trauma populations.

Cite This Study

A 1998 study studied this question.

synapsesocial.com/papers/6a7dcb32af21e1248e3c9c7chttps://doi.org/10.1177/026835559801300302
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Death and thromboembolic disease after total hip replacement. A series of 1162 cases with no routine chemical prophylaxis1995 · 230 citations
  2. 2Oral contraceptives and venous thromboembolism: findings in a large prospective study.1986 · 262 citations
  3. 3A Comparison of Low-Dose Heparin with Low-Molecular-Weight Heparin as Prophylaxis against Venous Thromboembolism after Major Trauma1996 · 813 citations
  4. 4Economic evaluation of standard heparin and enoxaparin for prophylaxis against deep vein thrombosis in elective hip surgery1994 · 74 citations
  5. 5Cost-effectiveness of Enoxaparin vs Low-Dose Warfarin in the Prevention of Deep-Vein Thrombosis After Total Hip Replacement Surgery1995 · 125 citations