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February 1, 1994Development

bcl-2 protein expression is widespread in the developing nervous system and retained in the adult PNS

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Authors

DMDiane E. MerryThomas Jefferson University DVDeborah J. VeisWashington University in St. Louis WHWilliam F. HickeyDartmouth–Hitchcock Medical Center

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Implication

bcl-2 expression suggests neuroprotection in developing neurons; leaves open therapeutic targeting in CNS disorders.

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Key points are not available for this paper at this time.

Cite This Study

Merry et al. (1994) studied this question.

synapsesocial.com/papers/6a7dd0601ec832c82ccdb113 https://doi.org/10.1242/dev.120.2.301

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Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

1Human homologue of murine T200 glycoprotein.1980 · 192 citations
2A negative regulatory element in the bcl-2 5'-untranslated region inhibits expression from an upstream promoter.1993 · 189 citations
3Cell Death During Development of the Nervous System1991 · 3,039 citations