Population
Isolated perfused rat hearts
Comparison
Isoprenaline, anoxia, insulin, and nicotinate vs Basal state
Design
Preclinical
Authors
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Myocardial cAMP release under stress may contribute to plasma levels; hypothesis-generating for human biomarker or therapeutic relevance.
The study demonstrates that the myocardium can release cyclic AMP in response to isoprenaline and anoxia, potentially contributing to plasma cyclic AMP levels.
O’Brien et al. (1975) studied this question.
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