Why the study?
Does the use of ACE inhibitors, ARBs, and/or statins reduce breast cancer recurrence in patients treated for stage II/III breast cancer?
Population
703 patients treated for stage II/III breast cancer between 1999 and 2005.
Comparison
ACE inhibitors, ARBs, and/or statins taken for… vs Patients not taking ACE inhibitors, ARBs, or…
Design
Cohort
Follow-up
median 55 months (maximal 118 months)
Authors
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Should not yet change practice; hypothesis-generating for ACEi/ARBs and statins reducing recurrence in stage II/III breast cancer.
Does the use of ACE inhibitors, ARBs, and/or statins reduce breast cancer recurrence in patients treated for stage II/III breast cancer?
The use of common cardiovascular medications, specifically ACE inhibitors, ARBs, and statins, is associated with a significantly reduced risk of breast cancer recurrence in patients with stage II/III disease.
Chae et al. (2011) studied this question.
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