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Background: Intracerebral Hemorrhage (ICH) is one of the most feared complications after brain tumor surgery.Postoperative hemorrhage has been described in presence of a reduction of Factor XIII (FXIII) with normal routine coagulation tests in different fi elds.The primary objetive was to evaluate the infl uence of perioperative FXIII levels on ICH after brain surgery.Methods: A prospective, observational, 18-month study was conducted at a third-level hospital in Spain.It included all consecutive adults (18 years of age or alder) operated on elective brain tumor surgery with postoperative stay in the Neurointensive Care Unit (N-ICU).Informed consent from all participants and ethical approval were obtained.Younger than 18 years of age, informed refusal, death in the OR, incomplete blood sample or non-tumoral tissue were exclusion criteria.
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Val et al. (2021) studied this question.
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