May 1, 1984British Journal of Haematology
Atherosclerosis and von Willebrand factor
Population
Individuals in Western European countries and Israel assessed for von Willebrand's disease, specifically…
Design
Cross-sectional
Authors
Discussion
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Member takes
Implication
Severe VWD prevalence varies markedly by region; leaves open its utility for registry-based atherosclerosis research.
Structured PICO
P
Population
Individuals in Western European countries and Israel assessed for von Willebrand's disease (VWD), specifically those with plasma levels of von Willebrand factor antigen less than 1 u/dl.
O
Outcome
Prevalence of severe von Willebrand's disease
The study establishes a registry of severe von Willebrand's disease patients in Western Europe and Israel, highlighting a 10-fold higher prevalence in Scandinavian countries to serve as a basis for future atherosclerosis research.
Cite This Study
Mannucci et al. (1984) studied this question.