December 15, 2016Advances in TherapyOpen Access

A Review of Clinical Practice Guidelines for the Management of Hypertriglyceridemia: A Focus on High Dose Omega-3 Fatty Acids

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Population

Individuals with high (200-499 mg/dL) and very high (≥500 mg/dL) triglyceride levels

Design

Review

Authors

DKDean G. KaralisTulane University

Discussion

Member takes

Implication

Supports guideline-directed lifestyle and TG-lowering therapy to prevent pancreatitis; leaves open optimal agents and thresholds for trials.

Structured PICO

Population

Individuals with high (200-499 mg/dL) and very high (≥500 mg/dL) triglyceride levels

Intervention

Management of hypertriglyceridemia including intensive lifestyle interventions and triglyceride-lowering medications (fibrates, niacin, or high-dose omega-3 fatty acids)

Outcome

Prevention of acute pancreatitis and cardiovascular disease

This review highlights that current clinical guidelines recommend lifestyle modifications and targeted pharmacotherapy, including high-dose omega-3 fatty acids, primarily to prevent acute pancreatitis in patients with severe hypertriglyceridemia.

Cite This Study

Dean G. Karalis (2016) studied this question.

synapsesocial.com/papers/6a7dd936cf7e8b32dacb5633 https://doi.org/10.1007/s12325-016-0462-y

Topics

Statin therapy Cardiovascular prevention

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Implication

Supports guideline-directed lifestyle and TG-lowering therapy to prevent pancreatitis; leaves open optimal agents and thresholds for trials.

A Review of Clinical Practice Guidelines for the Management of Hypertriglyceridemia: A Focus on High Dose Omega-3 Fatty Acids

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Topics

A Review of Clinical Practice Guidelines for the Management of Hypertriglyceridemia: A Focus on High Dose Omega-3 Fatty Acids

Discussion

Member takes

Implication

Structured PICO

Cite This Study

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Topics

Also Consider