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October 1, 2001HeartOpen Access

Treatment decision in asymptomatic aortic valve stenosis: role of exercise testing

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Why the study?

Does exercise testing predict sudden death or symptom development in asymptomatic patients with severe aortic stenosis?

Population

66 consecutive asymptomatic patients with isolated severe aortic stenosis (aortic valve area <= 1.0 cm2)

Comparison

Exercise testing and Doppler echocardiography vs Negative exercise testing

Design

Cohort

Follow-up

Mean 14.77 months

Authors

MAMarcelo Campos Moraes AmatoUniversidade de Ribeirão Preto

Discussion

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Implication

May aid risk stratification in asymptomatic severe AS; extends observational data but leaves open impact on intervention timing.

Structured PICO

Does exercise testing predict sudden death or symptom development in asymptomatic patients with severe aortic stenosis?

P
Population
66 consecutive asymptomatic patients with isolated severe aortic stenosis (aortic valve area <= 1.0 cm2)
I
Intervention
Exercise testing (evaluating ST segment depression, symptoms, ventricular arrhythmia, or inadequate rise of systolic blood pressure) and Doppler echocardiography
C
Comparator
Negative exercise testing
O
Outcome
Sudden death or the development of symptomscomposite

Exercise testing is safe and provides significant prognostic value for predicting sudden death or symptom onset in asymptomatic patients with severe aortic stenosis.

Cite This Study

Marcelo Campos Moraes Amato (2001) studied this question.

synapsesocial.com/papers/6a7ddb7e8b7e38892f150ea6https://doi.org/10.1136/heart.86.4.381
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Spontaneous course of aortic valve disease1987 · 415 citations
  2. 2Stress Testing: Principles and Practice.1988 · 377 citations
  3. 3Statistical Methods for Survival Data Analysis.1993 · 2,853 citations
  4. 4The natural history of adults with asymptomatic, hemodynamically significant aortic stenosis1990 · 394 citations