CRISPR/Cas9 targeting events cause complex deletions and insertions at 17 sites in the mouse genome

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1. 1Heterozygous mutation ofUsh1g/Sansin mice causes early-onset progressive hearing loss, which is recovered by reconstituting the strain-specific mutation inCdh232016 · 28 citations
2. 2Dual sgRNAs facilitate CRISPR/Cas9‐mediated mouse genome targeting2014 · 157 citations
3. 3Genome Engineering of Drosophila with the CRISPR RNA-Guided Cas9 Nuclease2013 · 1,079 citations
4. 4Large genomic fragment deletion and functional gene cassette knock-in via Cas9 protein mediated genome editing in one-cell rodent embryos2015 · 99 citations
5. 5Efficient CRISPR/Cas9-Mediated Genome Editing in Mice by Zygote Electroporation of Nuclease2015 · 313 citations