Why the study?
What is the physiological genesis of the third heart sound (IIIS)?
Population
31 cases with apparent third heart sound (IIIS)
Design
Cross-sectional
Authors
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Challenges mitral valve tension theory for S3; supports blood momentum arrest but leaves open prospective validation.
What is the physiological genesis of the third heart sound (IIIS)?
Phonoechocardiographic analysis demonstrates that the third heart sound is caused by the abrupt arrest of blood flow during rapid ventricular filling rather than mitral valve tension.
Sakamoto et al. (1976) studied this question.
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