December 19, 2012Scandinavian Journal of Gastroenterology

Serum angiopoietin-2 level as a predictor of tumor invasiveness in patients with hepatocellular carcinoma

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Population

33 patients with chronic liver disease who underwent a splanchnic hemodynamic study, median age 61 years…

Design

Cohort

Authors

ADAntonio Díaz‐SánchezHospital Universitario del Sureste AMAna MatillaHospital General Universitario Gregorio Marañón ÓNÓscar NúñezUniversidad San Pablo CEU

Discussion

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Implication

sAng-2 links to HCC invasiveness but not treatment response; hypothesis-generating for prognostic biomarkers, should not change practice.

Structured PICO

Population

33 patients with chronic liver disease who underwent a splanchnic hemodynamic study (32 received treatment for HCC), median age 61 years, 79% male. Main etiology Hepatitis C (70%), mostly Child-Pugh grade A (72.7%).

Intervention

Measurement of serum angiopoietin-2 (sAng-2) concentrations in peripheral and hepatic veins

Outcome

Association between sAng-2 levels and characteristics of tumor and liver diseasesurrogate

Serum angiopoietin-2 levels are associated with tumor characteristics and invasive behavior in patients with hepatocellular carcinoma, but do not predict or change with treatment response.

Cite This Study

Díaz‐Sánchez et al. (2012) studied this question.

synapsesocial.com/papers/6a7de1885d36433ac2187bfe https://doi.org/10.3109/00365521.2012.746391

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Serum angiopoietin-2 level as a predictor of tumor invasiveness in patients with hepatocellular carcinoma

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Serum angiopoietin-2 level as a predictor of tumor invasiveness in patients with hepatocellular carcinoma

Discussion

Member takes

Implication

Structured PICO

Cite This Study

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