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Studies were carried out with chickens and rats to relate the ingestion of medium- and long-chain saturated triglycerides to the blood and liver cholesterol level. It was found that MCT significantly elevated the plasma cholesterol level of chickens compared with LCT. The reverse observation was made in rats where MCT was effective in lowering serum cholesterol. On the other hand, MCT-fed chickens and rats had a significantly lower liver cholesterol level than LCT-fed individuals. The significance of these findings with reference to the relationship between dietary fat and blood lipid concentration is discussed.
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Fisher et al. (1964) studied this question.
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