Population
Endothelium-denuded cat pial arteries and brain parenchyma
Design
Preclinical
Authors
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Supports NO-mediated neurogenic relaxation in feline pial arteries; leaves open translation to human cerebral blood flow regulation.
Nitric oxide appears to play a key role in the neurogenic regulation of cerebral blood flow via local NADPH-diaphorase neurons innervating cerebral vessels.
Estrada et al. (1993) studied this question.
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