Why the study?
Does carotid endarterectomy increase the risk of medical complications compared to medical care alone in patients with symptomatic internal carotid artery stenosis?
Population
2,848 patients with symptomatic stenosis of the internal carotid artery from the North American Symptomatic…
Comparison
Carotid endarterectomy (CE) vs Medical care alone
Design
RCT
Follow-up
30 days
Authors
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CE triples perioperative medical complications versus medical therapy alone; confirms elevated risk in patients with prior MI, angina, or hypertension.
Does carotid endarterectomy increase the risk of medical complications compared to medical care alone in patients with symptomatic internal carotid artery stenosis?
Carotid endarterectomy is associated with an 8.1% rate of perioperative medical complications, mostly cardiovascular and resolving, which is approximately three times higher than medical therapy alone.
Paciaroni et al. (1999) studied this question.
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