PulseTrendingJournal ClubResearchersJournalsExplore
Instagram
HomeTrendingJournal ClubExplore
Synapse
⌘+K
Synapse
October 1, 1987Journal of Hypertension

Beta-Blockers Versus Diuretics in Hypertensive Men: Main Results from the HAPPHY Trial

View Full Paper
Ask AI
Bookmark
Share

Why the study?

Does beta-blocker based treatment reduce coronary heart disease events and death compared to thiazide diuretic based treatment in men with mild to moderate hypertension?

Population

6,569 men aged 40-64 years with mild to moderate hypertension. Excluded: patients with previous CHD, stroke…

Comparison

Beta-blocker based treatment, with additional… vs Thiazide diuretic based treatment, with…

Design

RCT, randomized

Follow-up

mean 45.1 months

Authors

LWLars WilhelmsenGBG BerglundDEDag Elmfeldt

Discussion

Loading...

Member takes

Overview

In men with mild to moderate hypertension, beta-blocker based therapy and thiazide diuretic based therapy are equally effective in preventing hypertensive complications including CHD and death.

Structured PICO

Does beta-blocker based treatment reduce coronary heart disease events and death compared to thiazide diuretic based treatment in men with mild to moderate hypertension?

P
Population
6,569 men aged 40-64 years with mild to moderate hypertension (diastolic blood pressure 100-130 mmHg). Excluded: patients with previous CHD, stroke, other serious diseases, or contraindications to diuretics or beta-blockers.
I
Intervention
Beta-blocker based treatment, with additional antihypertensive drugs added if normotension (DBP <95 mmHg) was not achieved.
C
Comparator
Thiazide diuretic based treatment, with additional antihypertensive drugs added if normotension (DBP <95 mmHg) was not achieved.
O
Outcome
Coronary heart disease (CHD) events and deathhard clinical

In men with mild to moderate hypertension, beta-blocker based therapy and thiazide diuretic based therapy are equally effective in preventing hypertensive complications including CHD and death.

Cite This Study

Wilhelmsen et al. (1987) studied this question.

synapsesocial.com/papers/6a7de9f9fcc540eda03c957dhttps://doi.org/10.1097/00004872-198710000-00009
View Full Paper
Ask AI
Bookmark
Share