Why the study?
Does perioperative clonidine reduce perioperative myocardial ischemic events in patients with or at risk of coronary arterial disease undergoing surgery?
Population
Patients with known, or at risk of, coronary arterial disease undergoing cardiac and noncardiac surgery
Comparison
Perioperative clonidine vs Placebo
Design
Meta-analysis
Follow-up
perioperative
Authors
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May warrant perioperative clonidine in at-risk patients; confirms ischemia reduction in meta-analysis.
Does perioperative clonidine reduce perioperative myocardial ischemic events in patients with or at risk of coronary arterial disease undergoing surgery?
Perioperative clonidine significantly reduces cardiac ischemic episodes in patients with or at risk of coronary artery disease without increasing bradycardia.
Nishina et al. (2002) studied this question.
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