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February 15, 2006Cancer ResearchOpen Access

Tumor Endothelial Cells Express Epidermal Growth Factor Receptor (EGFR) but not ErbB3 and Are Responsive to EGF and to EGFR Kinase Inhibitors

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Authors

DADhara N. AminKHKyoko HidaDBDiane R. Bielenberg

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Amin et al. (2006) studied this question.

synapsesocial.com/papers/6a7df42933dcb27c99cb62dbhttps://doi.org/10.1158/0008-5472.can-05-3387
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Neuregulin activation of ErbB receptors in vascular endothelium leads to angiogenesis1999 · 160 citations
  2. 2Increased<i>HER2</i>Gene Copy Number Is Associated With Response to Gefitinib Therapy in Epidermal Growth Factor Receptor–Positive Non–Small-Cell Lung Cancer Patients2005 · 371 citations
  3. 3Specificity within the EGF family/ErbB receptor family signaling network1998 · 813 citations
  4. 4Betacellulin induces angiogenesis through activation of mitogen‐activated protein kinase and phosphatidylinositol 3’‐kinase in endothelial cells2002 · 66 citations