Review reveals how vitamin A deficiency impairs immune defenses and increases infection risks in pediatric populations, highlighting the therapeutic importance of nutritional monitoring.
Vitamin A (VA), an essential micronutrient, plays a pivotal role in human growth, development, immune function, and vision. Vitamin A deficiency not only affects children's vision and growth, but also increases their susceptibility to infectious diseases, such as respiratory and gastrointestinal infections. Deficiency in vitamin A not only disrupts growth and development in children but also increases susceptibility to infectious diseases, such as respiratory and gastrointestinal infections. From an immunological standpoint, vitamin A is essential for the proper development and function of the immune system, with its deficiency impairing immune responses. Emerging evidence also suggests a role for vitamin A in the pathogenesis of systemic diseases, including metabolic and autoimmune disorders. Therefore, monitoring and managing vitamin A levels are of great significance in disease prevention and treatment. To fully understand the mechanism of vitamin A in various clinical diseases, it is important to provide a theoretical basis for improving the nutritional status of vitamin A to reduce the incidence of diseases and improve patient outcomes.
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Li et al. (2025) studied this question.
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