Why the study?
Does adequate surgical treatment and adjuvant chemotherapy improve survival and reduce recurrence in patients with malignant fibrous histiocytoma of bone?
Population
90 cases of malignant fibrous histiocytoma of bone. Staging: I B, II A, II B, III.
Comparison
Surgical treatment with or without adjuvant… vs Surgery alone vs surgery plus adjuvant…
Design
Case_series
Follow-up
up to 10 years
Authors
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May support adequate surgery plus adjuvant chemotherapy in MFH of bone; hypothesis-generating case report requiring prospective validation.
Does adequate surgical treatment and adjuvant chemotherapy improve survival and reduce recurrence in patients with malignant fibrous histiocytoma of bone?
Adequate surgical treatment combined with adjuvant chemotherapy improves survival in patients with malignant fibrous histiocytoma of bone, whereas inadequate surgery leads to high recurrence rates.
Capanna et al. (1984) studied this question.
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