Population
Cardiac cell networks (cell monolayers stained with Vm- (di-8-ANEPPS) or [Ca2+]i- (Fluo-3) sensitive dyes)
Design
Preclinical
Authors
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Supports low-cost LED-based fluorescence imaging in cardiac research; leaves open in vivo and clinical validation.
A novel, low-cost, all-solid-state system using high-power LEDs and fabricated emission filters provides stable and effective fluorescence imaging of electrical activity and calcium transients in cardiac cells with minimal photodamage.
Entcheva et al. (2004) studied this question.
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