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August 3, 1996BMJOpen Access

Prospective study of the role of cardiac troponin T in patients admitted with unstable angina

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Why the study?

Does positive troponin T status predict cardiac death, revascularisation, or non-fatal MI in patients admitted with unstable angina?

Population

460 patients admitted with chest pain, of which 183 had a final diagnosis of unstable angina

Comparison

Positive cardiac troponin T status vs Negative cardiac troponin T status

Design

Cohort, blinded

Follow-up

median of three years

Authors

PSPeter StubbsUniversity of Technology SydneyPCPaul CollinsonGeneral / Preventive / LipidsDMD. MoseleyWest Middlesex University Hospital

Discussion

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Implication

May support troponin T-based risk stratification in unstable angina; hypothesis-generating pending prospective validation.

Structured PICO

Does positive troponin T status predict cardiac death, revascularisation, or non-fatal MI in patients admitted with unstable angina?

P
Population
460 patients admitted with chest pain, of which 183 had a final diagnosis of unstable angina
I
Intervention
Positive cardiac troponin T status (measured 12-24 hours after admission)
C
Comparator
Negative cardiac troponin T status
O
Outcome
Cardiac death, need for coronary revascularisation, or readmission with non-fatal myocardial infarction as first eventshard clinical

Elevated troponin T in patients with unstable angina identifies a high-risk subgroup for subsequent cardiac events, aiding in risk stratification.

Cite This Study

Stubbs et al. (1996) studied this question.

synapsesocial.com/papers/6a7e054aa66bb49753045668https://doi.org/10.1136/bmj.313.7052.262
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The Prognostic Value of Serum Troponin T in Unstable Angina1992 · 960 citations
  2. 2Diagnostic performance and prognostic value of serum troponin T in suspected acute myocardial infarction1993 · 189 citations
  3. 3Troponin T for the Differential Diagnosis of Ischaemic Myocardial Damage1993 · 72 citations
  4. 4Diagnostic efficiency of troponin T measurements in acute myocardial infarction.1991 · 817 citations
  5. 5Prognosis in unstable angina.1976 · 56 citations