Why the study?
Does tissue Doppler imaging of the tricuspid annulus correlate with invasive hemodynamics in patients with suspected pulmonary hypertension?
Does tissue Doppler imaging of the tricuspid annulus correlate with invasive hemodynamics in patients with suspected pulmonary hypertension?
Tissue Doppler imaging of the tricuspid annulus, specifically Peak Sa, correlates strongly with invasive hemodynamics and can reliably predict low cardiac index in patients with suspected pulmonary hypertension.
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May aid noninvasive hemodynamic estimation in suspected PH; hypothesis-generating and requires prospective validation before clinical adoption.
The authors performed tissue Doppler imaging of the tricuspid annulus in patients with pulmonary hypertension to assess its correlation with invasive indices of right ventricular function. The study population consisted of 32 patients with suspected pulmonary hypertension who underwent pulsed tissue Doppler imaging of the tricuspid annulus and right heart catheterization. Peak systolic (Sa), early diastolic (Ea), and late diastolic (Aa) velocities of the lateral tricuspid annulus were measured and correlated with hemodynamic variables. Peak Sa demonstrated excellent correlation with hemodynamic variables, including cardiac index (r=0.78; P<.001), pulmonary vascular resistance (r=-0.79; P<.001), and transpulmonary gradient (r=-0.72; P<.001). Peak Sa <10 cm/s predicted cardiac index <2.0 L/min/m2 with 89% sensitivity and 87% specificity. In conclusion, tissue Doppler imaging of the tricuspid annulus is a complementary method to assess right ventricular function in pulmonary hypertensive patients.
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Rajagopalan et al. (2007) studied this question.
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