Why the study?
Does Polymyxin B-immobilized fiber hemoperfusion reduce plasma ANP and BNP levels in patients with septic shock?
Does Polymyxin B-immobilized fiber hemoperfusion reduce plasma ANP and BNP levels in patients with septic shock?
Polymyxin B-immobilized fiber hemoperfusion significantly reduces elevated plasma ANP and BNP levels in patients with septic shock, suggesting potential attenuation of cardiac dysfunction.
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PMX-F-associated ANP/BNP reductions may signal less cardiac strain in septic shock; hypothesis-generating, pending randomized outcome trials.
Nakamura et al. (2008) studied this question.
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