Why the study?
Enterovirus 71 has emerged as a major concern among children, creating a need to assess serostatus, identify risk factors for infection, and establish future vaccine policy.
Population
920 subjects including preschool children, 6-15-year-old students, and 16-50-year-old people in Taiwan
Comparison
EV71 serostatus across age groups and compared to rates in 1997, 1999, and 2007
Design
Seroepidemiology study
Authors
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Lower EV71 seropositivity signals heightened preschool susceptibility; leaves open vaccine need in evolving Taiwanese cohorts.
EV71 seropositive rates in Taiwanese children have significantly decreased over the past 20 years, leaving preschool children highly susceptible and highlighting the need for an EV71 vaccine.
Lee et al. (2019) studied this question.
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