Why the study?
Aspirin and clopidogrel are mainstays in secondary stroke prevention, but some patients do not demonstrate optimal antiplatelet effects.
Does pharmacist intervention paired with anti-platelet medication monitoring improve responsiveness to antiplatelet treatment in patients post-stroke or TIA?
Population
342 patients treated post-stroke or post-TIA at an outpatient neurology practice
Comparison
PFT with pharmacist intervention plus standard-of-care vs standard-of-care alone
Design
Retrospective matched chart review
Authors
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Pharmacist intervention with platelet testing may improve antiplatelet responsiveness post-stroke/TIA; leaves open need for randomized confirmation of outcomes.
Does pharmacist intervention paired with anti-platelet medication monitoring improve responsiveness to antiplatelet treatment in patients post-stroke or TIA?
Pharmacist intervention combined with platelet function testing significantly improves responsiveness to antiplatelet therapy and increases adherence counseling in patients post-stroke or TIA.
Gréger et al. (2020) studied this question.
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