Why the study?
What drugs have the potential to cause ischaemic stroke and how should their risks be managed?
What drugs have the potential to cause ischaemic stroke and how should their risks be managed?
Careful decision-making is required to weigh the risk-benefit profile of drugs that can cause ischaemic stroke on an individual patient basis.
Emphasizes individualized risk-benefit assessment for stroke-associated drugs; leaves open precise interaction effects in high-background-risk patients.
Summary There is a wide range of drugs with the potential to cause ischaemic stroke. Whilst the absolute risk of stroke with commonly used drugs is low, a patient's background risk of stroke can increase their chance of stroke in combination with a particular drug. Careful decision-making is required when initiating and continuing treatment to ensure the risk-benefit profile of a drug is weighed appropriately on an individual patient basis.
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Daniel Burrage (2019) studied this question.
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