Why the study?
Does amiodarone improve survival and reduce arrhythmic events in patients with VT/VF and organic heart disease implanted with an ICD?
Population
507 patients with ventricular tachycardia or fibrillation due to organic heart disease who had implantable…
Comparison
Amiodarone vs Class I anti-arrhythmic drug or control
Design
Cohort
Follow-up
mean 38+/-27 months
Authors
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Amiodarone was not associated with improved survival or event-free rates versus control in ICD patients; leaves open optimal antiarrhythmic selection for VT/VF.
Does amiodarone improve survival and reduce arrhythmic events in patients with VT/VF and organic heart disease implanted with an ICD?
In patients with ICDs for VT/VF, amiodarone did not significantly improve survival or arrhythmic event-free rates compared to control, though observational bias was noted.
Satomi et al. (2006) studied this question.
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