Why the study?
Does discontinuation of RAAS blockade improve eGFR in older CKD patients with renal artery stenosis and worsening renal failure?
Population
26 Caucasian patients with CKD and hemodynamically significant renal artery stenosis presenting with…
Design
Cohort
Follow-up
Mean 26.4 +/- 16.4 months
Authors
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May support considering RAAS blockade discontinuation in select older CKD patients; hypothesis-generating and requires randomized confirmation before practice change.
Does discontinuation of RAAS blockade improve eGFR in older CKD patients with renal artery stenosis and worsening renal failure?
Discontinuation of RAAS blockade in older CKD patients with renal artery stenosis and worsening renal failure can improve eGFR, though a subset still progresses to ESRD with high mortality.
Onuigbo et al. (2008) studied this question.
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