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October 12, 2004Anaesthesia

Effect of xenon anaesthesia on accuracy of cardiac output measurement using partial CO 2 rebreathing

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Why the study?

Does xenon-based anaesthesia affect the accuracy of cardiac output measurement using partial CO2 rebreathing compared to TIVA in patients undergoing aortic reconstruction?

Population

39 patients with ASA physical status III undergoing aortic reconstruction

Comparison

Xenon-based general anaesthesia vs Total intravenous anaesthesia (TIVA)

Design

RCT, Randomly assigned

Follow-up

Intraoperative

Authors

BBBerthold BeinSemmelweis UniversityPHPeeters HanneRHR. HanßKiel University

Discussion

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Implication

Partial CO2 rebreathing overestimates cardiac output during xenon anaesthesia; clinicians should avoid this method and researchers should validate alternatives in xenon settings.

Structured PICO

Does xenon-based anaesthesia affect the accuracy of cardiac output measurement using partial CO2 rebreathing compared to TIVA in patients undergoing aortic reconstruction?

P
Population
39 patients with ASA physical status III undergoing aortic reconstruction
I
Intervention
Xenon-based general anaesthesia
C
Comparator
Total intravenous anaesthesia (TIVA)
O
Outcome
Bias and precision of cardiac output measurement using partial CO2 rebreathing compared to echocardiography-derived measurementssurrogate

The NICO cardiac output monitor using partial CO2 rebreathing is inappropriate for determining cardiac output during xenon-based anaesthesia due to significant overestimation.

Cite This Study

Bein et al. (2004) studied this question.

synapsesocial.com/papers/6a7e2afcef3c205b104f96dfhttps://doi.org/10.1111/j.1365-2044.2004.03897.x
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Cardiac Output by Transesophageal Echocardiography Using Continuous-wave Doppler across the Aortic Valve1994 · 186 citations
  2. 2Intraoperative Determination of Cardiac Output Using Multiplane Transesophageal Echocardiography1998 · 182 citations
  3. 3Why measure cardiac output?2003 · 38 citations
  4. 4The effectiveness of right heart catheterization in the initial care of critically ill patients. SUPPORT Investigators1996 · 1,410 citations
  5. 5Effect of Ventilatory Settings on Accuracy of Cardiac Output Measurement Using Partial CO2Rebreathing2002 · 61 citations