Why the study?
Does the addition of irbesartan to amiodarone prevent recurrences in patients with lone atrial fibrillation?
Population
90 patients with an episode of persistent atrial fibrillation for >7 days, in the absence of cardiac or…
Comparison
Irbesartan 150 mg daily or 300 mg daily added to… vs Amiodarone 400 mg daily alone (n=30).
Design
RCT, randomised
Authors
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Supports irbesartan addition to amiodarone in lone AF post-cardioversion; extends evidence for ARBs in rhythm control.
Does the addition of irbesartan to amiodarone prevent recurrences in patients with lone atrial fibrillation?
The addition of high-dose irbesartan to amiodarone significantly reduces the rate of atrial fibrillation recurrences in patients with lone AF undergoing electrical cardioversion.
Hernández‐Madrid et al. (2004) studied this question.
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