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September 22, 2021Frontiers in SurgeryOpen Access

Conduits for Right Ventricular Outflow Tract Reconstruction in Infants and Young Children

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Authors

TQTao QianHYHaoyong YuanCCChunyang Chen

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Overview

Narrative review evaluates small-diameter conduits for right ventricular outflow tract reconstruction in infants, highlighting that current options lack growth potential despite adequate durability.

Key Points

  • To review the historical evolution, clinical performance, and limitations of small-diameter conduits (≤16 mm) used for pediatric right ventricular outflow tract reconstruction.
  • Synthesized contemporary and historical clinical literature on small-sized (≤16 mm) conduits for pediatric right ventricular outflow tract reconstruction.
  • Evaluated performance characteristics across homografts, bovine jugular vein conduits, expanded polytetrafluoroethylene, and emerging tissue-engineered scaffolds.
  • Homografts retain reliable long-term clinical track records, while bovine jugular vein conduits provide comparable durability and expanded polytetrafluoroethylene displays strong early outcomes in limited reports.
  • No existing conduit achieves lifelong durability or biological growth to match pediatric development, identifying cell-free tissue-engineered scaffolds as the leading candidate for future development.

Cite This Study

Qian et al. (2021) studied this question.

synapsesocial.com/papers/6a7e30dad2dab736758561a7https://doi.org/10.3389/fsurg.2021.719840
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Use of an expanded polytetrafluoroethylene valved patch with a sinus in right ventricular outflow tract reconstruction†2019 · 12 citations
  2. 2A European study on decellularized homografts for pulmonary valve replacement: initial results from the prospective ESPOIR Trial and ESPOIR Registry data†2019 · 75 citations
  3. 3Use of Fresh Decellularized Allografts for Pulmonary Valve Replacement May Reduce the Reoperation Rate in Children and Young Adults2011 · 220 citations
  4. 4Polytetrafluoroethylene pulmonary valve conduit implantation for chronic pulmonary insufficiency2014 · 13 citations
  5. 5Decellularized fresh homografts for pulmonary valve replacement: a decade of clinical experience2016 · 160 citations