Influence of autonomic neuropathy, systemic inflammation and other clinical parameters on mortality in dialysis patients

Figures

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  Figure 1:. Autonomic neuropathy and possibly affected organ systems (with permission from www.intolife.in).

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  Figure 2:. a: Kaplan–Meier survival curve for dialysis patients (n = 112) in dependence on AN scores during a 5-year interval; dichotomization of groups: red = group with the higher 50% of AN scores, blue = group with the lower 50% of AP scores. Under the curve: No. at risk for each group; survival after 5 years: 30% (95% CI 18 to 42) and 48% (95% CI 35 to 61), respectively (p < 0.05). b: Kaplan–Meier survival curve for dialysis patients (n = 111) in dependence on CRP levels during a 5-year interval; dichotomization of groups: red = group with the higher 50% of CRP, blue = group with the lower 50% of CRP. Under the curve: No. at risk for each group; survival after 5 years: 27% (95% CI 15 to 39) and 52% (95% CI 39 to 65), respectively (p < 0.01).

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  Figure 3:. a: Kaplan–Meier survival curve for dialysis patients (n = 112) in dependence on sex during a 5-year interval; dichotomization of groups: red = men (n = 68), blue = women (n = 44). Under the curve: No. at risk in each group; survival after 5 years: 29% (95% CI 18 to 40) and 55% (95% CI 41 to 69), respectively (p < 0.01). b: Kaplan–Meier survival curve for dialysis patients (n = 112) in dependence on age during a 5-year intervall; dichotomization of groups: red = group with the older 50% of patients, blue = group with the younger 50% of patients (mean = 71.5 years). Under the curve: No. at risk for each group; survival after 5 years: 20% (95% CI 10 to 30) and 59% (95% CI 46 to 72), respectively (p < 0001).

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  Figure 4:. a: Kaplan–Meier survival curve for dialysis patients (n = 112) in dependence on diagnosis of diabetes during a 5-year interval; red = with diabetes (n = 55), blue = without diabetes (n = 57). Under the curve: No. at risk for each group; survival after 5 years: 27% (95% CI 16 to 38) and 51% (95% CI 38 to 64), respectively (p < 0.05). b: Kaplan–Meier survival curve for dialysis patients (n = 112) in dependence on BMI during a 5-year interval; dichotomization of groups: red = group with the higher 50% of BMI, blue = group with the lower 50% of patients. Under the curve: No. at risk for each group; survival after 5 years: 39% in both groups (n.s.). (95% CI 28 to 50 for higher BMI group and (95% CI 24 to 54 for lower BMI group).