Field potentials from cardiomyocyte monolayers can reliably estimate repolarization characteristics (APD50, APD90) when T waves are biphasic, while LEAP potentials estimate APD90 but do not accurately reflect the full local action potential.
We present a physiological basis for the interpretation of multielectrode array-derived, extracellular, electrical signals.
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Ernault et al. (2024) studied this question.
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