Echocardiographic Evaluation of Diastolic Function in Asymptomatic Type 2 Diabetes and Relation With Duration of Dm

INTRODUCTION heart failure is the final result of cardiovascular complications in diabetes mellitus, in which the diastolic dysfunction impaired earlier than the systolic function. Diastolic dysfunction may be asymptomatic without signs of overt heart failure. cross-sectional hospital based study was done which included 50 asymptomatic patients with type 2 diabetes without evidence coronary artery disease, congestive heart failure or thyroid disease. LV diastolic dysfunction was evaluated by Doppler , which included the Valsalva manoeuvre to unmask the pseudonormal pattern of left ventricular filling. The of diastolic dysfunction and the associated risk factors were assessed. was found in 35 subjects (71%), of whom 30 had impaired relaxation and 5 had a pseudonormal pattern of ventricular . Systolic function was normal in all subjects, and there was no correlation between LVDD and indexes of metabolic . It was also found that age ≥46 years was associated with an almost three times higher risk for the development of dysfunction in type 2 diabetes. Especially females were at two times higher risk of developing diastolic dysfunction when compared to men. Duration of diabetes ≥ two and half years was associated with a two times higher risk for diastolic dysfunction. Diastolic dysfunction is much more common than previously assumed in subjects with well-controlled type 2 diabetes who without any clinically detectable cardiac disease. The high prevalence of this phenomenon in this high-risk population that screening for LVDD in type 2 diabetes should be routinely done & must include procedures such as the Valsalva to unmask a pseudonormal pattern of ventricular filling.