Population
Live cells expressing green fluorescent protein-Kv1.4 fusion proteins and COOH-terminal variants
Comparison
Coexpression with PSD-95 vs Expression of Kv1.4 variants without PSD-95 or…
Design
Preclinical
Authors
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Animal findings distinguish immobilization from clustering; leaves open translation to human cardiac K+ channel function.
This study demonstrates for the first time that PSD-95 immobilizes target K+ channels and that the structural requirements for clustering and immobilization are distinct.
Burke et al. (1999) studied this question.
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