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June 15, 1996Journal of Clinical InvestigationOpen Access

Mechanisms of drug-induced lupus. II. T cells overexpressing lymphocyte function-associated antigen 1 become autoreactive and cause a lupuslike disease in syngeneic mice.

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Authors

RYRaymond YungUniversity of MichiganDPDaniel PowersAVEO Oncology (United States)KJK J JohnsonThe Ohio State University Wexner Medical Center

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Cite This Study

Yung et al. (1996) studied this question.

synapsesocial.com/papers/6a7e499bdea41f5fbab7b1bahttps://doi.org/10.1172/jci118743
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Accessory molecules and T cell activation I. Antigen receptor avidity differentially influences T cell sensitivity to inhibition by monoclonal antibodies to LFA‐1 and L3T41986 · 21 citations
  2. 2Lymphocyte function—associated antigen 1 overexpression and t cell autoreactivity1994 · 123 citations
  3. 3A systemic lupus erythematosus (SLE)‐like disease in mice induced by abnormal T‐B cell cooperation. Preferential formation of autoantibodies characteristic of SLE1982 · 277 citations
  4. 4Evidence for impaired t cell dna methylation in systemic lupus erythematosus and rheumatoid arthritis1990 · 565 citations
  5. 5Evidence that macrophages are programmed to die after activating autologous, cloned, antigen‐specific, CD4+ T cells1993 · 33 citations