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The members of the Genomics Workgroup in the Electronic Medical Records and Genomics (eMERGE) network (Gottesman et al., 2013) led the development of a Special Topic in Frontiers in Genetics titled “Genetics Research in Electronic Health Records Linked to DNA Biobanks1.” The goal was to publish papers representing the diverse research ongoing in the integration of electronic health records (EHR) with genomics through basic, clinical, and translational research. The special topic with its 18 papers is extremely timely given the recent announcement of the Precision Medicine initiative by the White House2, which includes the potential to build a biobank of 1 million Americans with rich, phenotypic data—likely from EHR. eMERGE has, therefore, served as an excellent test case for how a 1 million person project might work across several medical centers, EHR systems, and genetic datasets.
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Ritchie et al. (2015) studied this question.
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