Why the study?
Does thrombolysis with or without first rib resection improve long-term quality of life and reduce persisting symptoms in patients with primary subclavian vein thrombosis compared to oral anticoagulation alone?
Population
45 consecutive patients with primary (spontaneous or effort related) subclavian vein thrombosis (PSVT)
Comparison
Thrombolysis followed by anticoagulant therapy… vs Oral anticoagulant therapy only (n=14)
Design
Case-control
Follow-up
mean 57 months (range 2-176, SD ± 46)
Authors
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Anticoagulation alone may suffice for long-term QoL in primary subclavian vein thrombosis; leaves open need for randomized confirmation.
Does thrombolysis with or without first rib resection improve long-term quality of life and reduce persisting symptoms in patients with primary subclavian vein thrombosis compared to oral anticoagulation alone?
Thrombolysis with or without first rib resection does not provide long-term improvement in symptoms or quality of life compared to anticoagulation alone in patients with primary subclavian vein thrombosis.
Bosma et al. (2011) studied this question.
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