Why the study?
Does dopamine alter myocardial action potentials and contractions in pig myocardium at normothermia and hypothermia?
Does dopamine alter myocardial action potentials and contractions in pig myocardium at normothermia and hypothermia?
Dopamine increases contractile force and prolongs action potential duration in porcine myocardium at both normothermic (37°C) and hypothermic (32°C) conditions.
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Caution against clinical extrapolation from porcine data; leaves open translational studies on dopamine in hypothermic myocardium.
Roscher et al. (2001) studied this question.
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