What question did this study set out to answer?

Investigate the metabolic pathways and kinetics of strontium and calcium in patients with metabolic bone disorders using radioactive tracer isotopes.

June 1, 1960Journal of Clinical InvestigationOpen Access

Strontium and Calcium Metabolism in Metabolic Bone Diseases *

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Authors

EDElias C. DowMassachusetts General Hospital JSJohn B. StanburyUniversity of North Carolina at Chapel Hill

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Implication

Tracer kinetic study demonstrates radioactive calcium emission properties in metabolic bone diseases, suggesting reliable parameters for skeletal mineral turnover.

Key Points

Investigate the metabolic pathways and kinetics of strontium and calcium in patients with metabolic bone disorders using radioactive tracer isotopes.
Obtained calcium-45 radioisotopes from Oak Ridge National Laboratory for metabolic tracing.
Characterized the radiation profile and kinetic decay parameters of the calcium radioisotope.
Determined that the calcium isotope exclusively emits beta rays with an average energy of 0.100 MeV.
Measured a physical radioactive half-life of 163 days for the isotopic tracer.

Cite This Study

Dow et al. (1960) studied this question.

synapsesocial.com/papers/6a7e5cd5e26c9db0b64d9090 https://doi.org/10.1172/jci104109

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Implication

Tracer kinetic study demonstrates radioactive calcium emission properties in metabolic bone diseases, suggesting reliable parameters for skeletal mineral turnover.

Strontium and Calcium Metabolism in Metabolic Bone Diseases *

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Member takes

Implication

Key Points

Cite This Study

Strontium and Calcium Metabolism in Metabolic Bone Diseases *

Discussion

Member takes

Implication

Key Points

Cite This Study

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