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January 1, 2000Thrombosis and Haemostasis

Plasma Concentration of von Willebrand Factor in Acute Myocardial Infarction

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Population

51 patients with acute myocardial infarction

Design

Cohort

Follow-up

14 days (in a subset of 10 patients)

Authors

JKJaeyoung KimKorea UniversityNANaoto AokiTokai UniversitySASumihisa AbeTokai University

Discussion

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Implication

Elevated vWF at AMI onset should not yet change practice; leaves open its prognostic or therapeutic utility.

Structured PICO

P
Population
51 patients with acute myocardial infarction
C
Comparator
Age-matched control group
O
Outcome
Plasma concentration of von Willebrand factor (vWF)surrogate

Plasma vWF concentrations are significantly elevated in acute myocardial infarction and correlate with hemodynamic deterioration.

Cite This Study

Kim et al. (2000) studied this question.

synapsesocial.com/papers/6a7e5e10ef8e9536aa85658ehttps://doi.org/10.1055/s-0037-1613997
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1von Willebrand factor in plasma: a novel risk factor for recurrent myocardial infarction and death.1991 · 362 citations
  2. 2Early Increase of von Willebrand Factor Predicts Adverse Outcome in Unstable Coronary Artery Disease1998 · 252 citations
  3. 3Distinct mechanisms of platelet aggregation as a consequence of different shearing flow conditions.1998 · 286 citations
  4. 4Epinephrine Induces von Willebrand Factor Release from Cultured Endothelial Cells: Involvement of Cyclic AMP-dependent Signalling in Exocytosis1997 · 108 citations