Why the study?
Does Polycystic Ovarian Disease (PCOD) alter lipid profiles and metabolic markers in primary infertile women compared to those with normal pelvic studies?
Does Polycystic Ovarian Disease (PCOD) alter lipid profiles and metabolic markers in primary infertile women compared to those with normal pelvic studies?
Women with PCOD exhibit significant dyslipidemia and metabolic alterations compared to normal controls, highlighting their predisposition to metabolic syndrome and future cardiovascular risk.
PCOD was associated with dyslipidemia and metabolic changes in infertile women; leaves open cardiovascular risk implications and need for prospective validation.
Polycystic ovarian syndrome is the most common form of anovulatory infertility. Associated with the prevalent insulin resistance, these women exhibit a characteristic dyslipidaemia and a predisposition to non-insulin dependent diabetes and cardiovascular disease in later life. Thus, polycystic ovarian syndrome seems to have many of the hallmarks of the metabolic syndrome. In view of this a comparative study of lipid profile was done in primary infertile women with PCOD and primary infertile women with normal pelvic study. This study enrolled 25 PCOD women and 25 normal women of age 20 -35 years. Pearsons correlation co efficiencies were used to compare the correlations. It showed significant raise in waist circumference, fasting blood glucose level in women with PCOD than in women with normal study (controls). This study showed significant raise in total cholesterol, triglycerides and raise in ratio of TTG/HDL-C, decrease in levels of HDL-C in PCOD women.
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Latha et al. (2014) studied this question.
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